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PUBLICATIONS

The Fruits of My Labor

Expect the unexpected in research. Each project I work on comes with both unforeseeable challenges and opportunities. Many of the papers I’ve published were born out of experiments performed on the fly or purely for curiosity's sake. Check out the list of my publications below, and don’t hesitate to contact me for more information.

Publications: Publications

  1. Rai, M. F., Wu, C. L., Capellini, T. D., Guilak, F., Dicks, A. R., Muthuirulan, P., ... & Westendorf, J. J. (2021). Single Cell Omics for Musculoskeletal Research. Current Osteoporosis Reports, 1-10.

  2. Muthuirulan, P. (2020). CRISPR: a molecular scissor set to change the world. Drug Target Review. (Issue 4).(Magazine).

  3. Muthuirulan, P. (2020). Genetic screening to predict the risk of future diseases. Drug Target Review. (Issue 4). (Magazine).

  4. Magana, M., Muthuirulan p., Santos, A. L., Leanse, L., Fernandez, M., Ioannidis, A., ... & Cherkasov, A. (2020). The value of antimicrobial peptides in the age of resistance. The Lancet Infectious Diseases. Volume 20, Issue 9, e216-e230.

  5. Richard, D., Liu, Z., Cao, J., Kiapour, A. M., Willen, J., Yarlagadda, S., ... & Muthuirulan, P, et al (2020) Evolutionary Selection and Constraint on Human Knee Chondrocyte Regulation Impacts Osteoarthritis Risk. Cell. Volume 181, Issue 2, 362-381.e28.

  6. Muthuirulan, P. (2020). NGS: offering a glimmer of hope in the fight against COVID-19. Drug Target Review (Issue 3). (Magazine).

  7. Christdas, J., & Muthuirulan P. (2020). COVID-19 Prophylaxis: The Desperate Need for Mankind. J Pure Appl Microbiol, 14(suppl 1), 695-698.

  8. Muthuirulan, P. (2020). Genomic assays: on the brink of revolutionising human healthcare. Drug Target Review (Issue#1) 11-13. (Magazine).

  9. Muthuirulan, P. (2019). CRISPR: kick-starting the revolution in drug discovery. Drug Target Review. (Issue#4) 19-22.

  10. Muthuirulan, P., & Capellini, T. D. (2019). Complex Phenotypes: Mechanisms Underlying Variation in Human Stature. Current osteoporosis reports, 1-23.

  11. Muthuirulan, P. (2019). Genomic medicine: cracking genomes to cure ‘incurable’ diseases. Drug Target Review. (Issue#3) 32-34. (Magazine).

  12. Muthuirulan, P. (2019). Personal genomics: the fast track to “precision medicine”. Drug Target Review. (Issue#2) 5. (Magazine).

  13. Muthuirulan, P. (2019). Realizing the promise of laboratory automation in biomedical research. Drug Target Review. (Issue#1) 30-32. (Magazine).

  14. Muthuirulan, P. (2019). Functional Medicine: A Holistic Treatment Approach to the Peaceful Healing Journey.Vol.5 (1), The Journal of Health and Human Experience. 50-58.

  15. Muthuirulan, P. (2018). Omics-informed drug target discovery in combating emerging infectious diseases. Drug Target Review. (Issue#4) 50-52. (Magazine).

  16. Muthuirulan, P. (2018). The changing face in drug discovery. Drug Target Review. (Issue#3) 5. (Magazine).

  17. Muthuirulan, P. (2018). Next-Generation Sequencing: Hunting mysterious ‘Dark Matter Genome’ towards rewriting the rules of human genetic diseases. Drug Target Review. (Issue#3) 72-75. (Magazine).

  18. Muthuirulan, P. (2018). Unexpected Role of Nitric Oxide Signals in Myometrial Relaxation: A Promising Therapeutic Approach in Preterm Birth Prevention. Journal of Postdoctoral Research. May 37, 38.

  19. Muthuirulan, P (2018). Hurting Antibiotics-A Cautionary Tale to Save Human Lives. Clinical Infectious Diseases: Open Access, 2: e102. 

  20. Muthuirulan, P. (2018). Do Microbes Care About Human Heart. J Infect Dis Immune Ther 2, 1, 2. 

  21. Muthuirulan, P (2018) Lab automation and robotics – accelerating the pace of antimicrobial therapy. Drug Target Review. (Issue#1) 6-8. (Magazine).

  22. Bandyopadhyay, M., & Muthuirulan, P. (2018). Promising Targets for Prospective Antibacterial Therapy. EC Microbiology, 14, 351-360.

  23. Velmurugan G, Ramprasath T, Swaminathan K, Mithieux G, …., Rajmohan RK; Velayutham K; Lyon AR; Ramasamy S (2017) Gut microbial degradation of organophosphate insecticides-induces glucose intolerance via gluconeogenesis. Genome biology, 18(1), 1-18.18:8. DOI10.1186/s13059-016-1134-6.

  24. Muthuirulan, P (2017) CRISPR Inspires New Hope to Disease Sufferers. Journal of Molecular Microbiology.Vol.1 No.1:8.

  25. Muthuirulan, P (2017). Flow Cytometry: accelerating neuroscience research. Drug Target Review (Issue#3) (Magazine).

  26. Bandyopadhyay M and Muthuirulan, P (2017) Androgen Signaling: Promising Target for Prospective Cancer Therapy. Journal of Drug Design and Development. 1:1, DOI: 10.36959/426/603

  27. Muthuirulan, P, Pooja S (2017) Next-Generation Sequencing: Empowering Infectious Disease Research Far Beyond Reality. Drug Target Review (Issue#3) (Magazine).

  28. Muthuirulan, P (2017) CRISPR-Cas9: Promising platform for prospective antimicrobial therapy. Advanced Techniques in Clinical Microbiology. Vol.1 No.1:6.

  29. Muthuirulan, P (2017) Lethal ovitrap: A cost-effective weapon to fight zika virus infection. Virology: Research & Reviews (VRR)Vol.1: 2-2.

  30. Muthuirulan, P and Arun Richard C (2016) Microbial flow Cytometry: An Ideal Tool for Prospective Antimicrobial Drug Development. Analytical Biochemistry: Methods in the Biological Sciences. doi:10.1016/j.ab.2016.05.025 (Technical note).

  31. Muthuirulan, P (2016) Insight into phenotypic and genotypic discrimination of bacterial pathogens: From Pre-Genomic to Post-Genomic Era. BAOJ Med Nursing 2: 018 (Review article).

  32. Arun Richard C,  and Havorsen K (2016) Evolution of DNA Origami Scaffolds. Materials Letters. 170: 221-224. doi:10.1016/j. matlet.2016.01.161.

  33. Muthuirulan, P (2016) Versatile applications of next-generation sequencing in pharmaceutics. Drug Target Review. Issue#4 (Magazine).

  34. Muthuirulan, P (2016) Chasing new drugs against infectious diseases − A herculean task. Journal of Clinical Case reports. 6:859. doi: 10.4172/2165-7920.1000859.

  35. Muthuirulan, P, Pooja S (2016) Flow cytometry: breaking bottlenecks in drug discovery and development. Drug Target review. Issue#3 (Magazine).

  36. Muthuirulan, P. Integrating Omics Technologies for Prospective Antimicrobial Drug Development. (2016) J Cell Biol Mol Sci 1(1): 1-7.

  37. Muthuirulan, P (2016) Protect Your Microbiome to Stay Healthy and Disease-Free Life. EC Microbiology 3.4: 482- 484.

  38. Muthuirulan, P (2016) Metagenome- Massive Reservoir of Antifungal Peptides to Treat Emerging Infections. EC Proteomics and Bioinformatics ECO.01: 05-06.

  39. Muthuirulan, P (2016) Era of Antimicrobials: Winning Microbes! Journal of Bacteriology & Mycology: Open Access 2(2): 00021.

  40. Muthuirulan, P (2016) Leaky Gut Syndrome: mystery illness triggered by Candida albicans. Journal of Nutrition Health and Food Engineering 4(3): 00133. DOI:10.15406/jnhfe.2016.04.00133.

  41.  Pushpanathan M, Pooja S, Gunasekaran P and Rajendhran J (2016) Critical evaluation and compilation of physicochemical determinants and membrane interactions of MMGP1 antifungal peptide. Molecular Pharmaceutics. 13(5), 1656-1667. DOI: 10.1021/acs.molpharmaceut.6b00086

  42. Pushpanathan M, Manjula A, Sathyavathi S, Gunasekaran P and Rajendhran J (2015) Comparative analysis of microbial diversity in termite gut and termite nest using Ion-sequencing. Current Microbiology doi:10.​1007/​s00284-015-0947-y [Epub ahead of print].

  43. Pooja S, , Gunasekaran P and Rajendhran J (2015) Cytoskeleton mediated invasion and pathogenecity of in rat cardiomyocytes.  2;10(10): e0139733. doi: 10.1371/journal.pone.0139733 

  44. Ranjani J, , Mahesh A, Niraimathi M, Gunasekaran P and Rajendhran J (2015)  PAO1 induces distinct cell death mechanisms in H9C2 cells and its differentiated form.  Doi: 10.1002/jobm.201500037

  45. Pooja S, , Jayashree S, Gunasekaran P and Rajendhran J (2014) Identification of periplasmic α-amlyase from cow dung metagenome by product induced gene expression profiling (pigex). , 1-9

  46. Jayashree S, Pooja S, , Rajendhran J, Gunasekaran P (2014) Identification and characterization of bile salt hydrolase genes from the genome of MTCC 8711. 174.2: 855-866 

  47. Dinakaran V, Rathinavel A, , Sivakumar R, Gunasekaran P, Rajendhran J (2014) Elevated levels of Circulating DNA in Cardiovascular disease patients: Metagenomic profiling of Microbiome in the Circulation.  , 9(8), e105221 

  48. Manjula A, Sathyavathi S, , Gunasekaran P and Rajendhran J (2014) Microbial diversity in termite nest,  (00113891), 106(10) 

  49. Pushpanathan M, Gunasekaran P, Rajendhran J. (2014) Microbial bioremediation: A metagenomics approach. Microbial Biodegradation and Bioremediation, Elsevier publication, ISBN: 978-0-12-800021-2 .

  50. Pushpanathan M, Gunasekaran P and Rajendhran J (2013) Mechanisms of the antifungal action of marine metagenome-derived peptide, MMGP1, against Candida albicans PLoS ONE, 8(7): e69316, doi:10.1371/journal. pone.0069316.

  51. Pushpanathan M, Gunasekaran P and Rajendhran J (2013) Antimicrobial peptides: Versatile biological properties. International Journal of Peptides, doi.org/10.1155/2013/675391.

  52. Pushpanathan M, Gunasekaran P, Rajendhran J (2013) Proteolytic activity of marine metagenome derived antifungal peptide, MMGP1, International Journal of Peptide Research and Therapeutics, 19(4), 331-336 DOI 10.1007/s 10989-013-9351-2.

  53. Jayashree S, , Rajendhran J and Gunasekaran P, (2013) Microbial diversity and phylogeny analysis of buttermilk, a fermented milk product, employing 16S rRNA-based pyrosequencing, , 27: 213-221

  54. Jayashree S, Pooja S, , Vishnu US, Sankarasubramanian J, Rajendhran J, and Gunasekaran P (2013) Genome sequence of  MTCC 8711, a probiotic bacterium isolated from yoghurt, , 1: e00770-13.

  55. Pushpanathan M, Rajendhran J, Jayashree S, Sundarakrishnan B, Jayachandran S, Gunasekaran P, (2012) Direct cell penetration of antifungal peptide, MMGP1 in Candida albicans, Journal of Peptide Sciences, 8: 657-660.

  56. Pushpanathan M, Rajendhran J, Jayashree S, Sundarakrishnan B, Jayachandran S, Gunasekaran P, (2012) Identification of a novel antifungal peptide with chitin-binding property from marine metagenome Proteins and Peptide Letter, 19:1289-1296.

  57. Sundarakrishnan B, Jayashree S, Rajendhran J, Sakthivel N, Jayachandran S, Gunasekaran P, (2012) Assessment of Microbial Richness in Pelagic Sediment of Andaman Sea by Bacterial Tag Encoded FLX Titanium Amplicon Pyrosequencing (bTEFAP). , DOI 10.1007/s12088-012-0310-y 

  58. Pushpanathan M, Pandian RS. (2009) “Culture filtrate of Pseudomonas fluorescens Migula Pseudomonadales: Pseudomonadaceae) an ideal ovitrap agent for the Vectors ofdengue and chikungunya, Aedes aegypti (Linn) and Aedes albopictus (Skuse), Current Biotica, 2:461-471.

  59. Pushpanathan M, Pandian RS, (2008) Management of dengue and chikungunya vectors Aedes aegypti (Linn) and Aedes albopictus (Skuse)(Diptera:Culicidae) by the exotoxin of  Pseudomonas fluorecens Migula  (Pseudomonadales: Pseudomonadaceae), Current Biotica, 2:74-103 (Research article).

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