Flow Cytometry: Accelerating Neuroscience Research

Flow cytometry continue to evolve at a fast pace and provides neuroscientists the capability for performing many of highly-specialized assays simultaneously. Flow cytometry meet the demands of cutting edge research in neuroscience that has allowed researchers to isolate particular neural cells from heterogeneous population and catalog its molecular or physical features. With the development of greater throughput and sensitivity, flow cytometry has become the unique tools for characterizing surface or internal antigen expression of neural cells, rapid sorting of activated neurons, assessment of neurochemical components, understanding neural morphology and cell density changes during pathophysiology of neurological disorders. The continuous expansion of flow cytometric techniques to assess the intracellular changes within neural cells such as calcium influx, cellular reactive oxygens species generation and activation of apoptosis are moving this technology into the arena of studying brain disorders. All these approaches are expanding the utility of flow cytometry as a valuable tool for neurological examination to assess the impact of neurological damage towards developing novel therapeutics to treat neurological disorder.

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https://www.drugtargetreview.com/article/25369/drug-target-review-issue-3-2017/